A low cost of living can significantly impact quality of life and financial well-being. In the United States, the southern and central regions provide the most cost-effective lifestyle, with a lower than average Cost of Living Index. This index measures the relative cost of living across the states, considering variables like housing, transportation, healthcare, food, childcare, and taxes. The national average for each index is 100, so an index value lesser than 100 means the costs are lower than the national average.